Instructional Course: Saving the Bladder in Muscle-Invasive Bladder Cancer: Multidisciplinary Tips and Tricks

Thursday, November 12, 2026

16:00 - 17:30 CET

Chair(s)

Gagan Prakash

Uro-oncologist
Tata Memorial Hospital, Homi Bhabha National Institute, India

Saving the bladder in muscle-invasive bladder cancer (MIBC) requires careful patient selection and close multidisciplinary collaboration. This instructional course will provide a practical, case-based framework for implementing bladder preservation strategies using maximal TURBT, systemic therapy, and radiation. Through integrated perspectives from urology, medical oncology, and radiation oncology, participants will learn technical and clinical "tips and tricks" for optimizing outcomes while minimizing toxicity. Topics will include patient selection, neoadjuvant and concurrent systemic therapy, modern radiation techniques, intravesical approaches, surveillance strategies, use of biomarkers such as ctDNA, and indications for salvage cystectomy. Emphasis will be placed on real-world decision-making and multidisciplinary coordination.

Learning Objectives:

At the end of this session, attendees should be able to:

Identify appropriate candidates for bladder preservation in muscle-invasive bladder cancer using clinical, pathologic, and patient-specific factors.
Describe the roles of urology, medical oncology, and radiation oncology in delivering bladder-preserving therapy, including maximal TURBT, systemic therapy selection, and radiation technique, dose, and fractionation.
Apply practical strategies to minimize toxicity, monitor response, and manage complications
Implement a multidisciplinary treatment algorithm for bladder preservation in routine clinical practice, integrating emerging systemic therapies and modern radiation approaches.

Presentations:

16:00 - 16:05 CET

Welcome
16:05 - 16:20 CET

Urology Perspective - Maximal TURBT, Intravesical Strategies, And Salvage Cystectomy
16:20 - 16:35 CET

Medical Oncology Perspective - Systemic Therapy And Biomarker-Guided Management
16:35 - 16:50 CET

Radiation Oncology Perspective - Radiation Technique, Dose, And Fractionation
16:50 - 17:15 CET

Multidisciplinary Case Panel - Real-World Decision Making: When And How To Save The Bladder
17:15 - 17:30 CET

Closing Remarks and Open Discussion