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Surgery Day
Surgery Day
Bench to Bedside
Bench to Bedside
SIU@U
SIU@U

    Track: Penile/Urethra Cancer
    Session Type: Hot Topic

    Hot Topic: From Urethra to Groin - High-Stakes Decisions in Rare GU Cancers

    Friday, November 13, 2026
    15:15 - 16:45 CET

      Chair(s)

    • Philippe Spiess

      MD, MS, FRCS(C), FACS Chief of Clinical Innovation Assistant Chief of Surgical Services Senior Member, Dept of GU Oncology
      Moffitt Cancer Center, United States

    Learning Objectives:

    At the end of this session, attendees should be able to:
    • Apply an evidence-based diagnostic and staging pathway for primary urethral carcinoma, tailored by sex, tumour location, and histology.
    • Select appropriate definitive treatment strategies for urethral carcinoma (organ-sparing, extirpative surgery, radiotherapy/chemoradiotherapy) based on stage, anatomy, and patient factors.
    • Critically compare pelvic management strategies in high-risk node-positive penile cancer after ILND, including pelvic lymph node dissection versus adjuvant pelvic radiotherapy/chemoradiotherapy or observation.
    • Formulate an adjuvant strategy after ILND in high-risk penile cancer, including when to consider radiotherapy to the groins (± pelvis) using contemporary trial-informed principles (e.g., InPACT frameworks).
    • Recognise actionable systemic therapy and biomarker developments in penile cancer and identify patients suitable for early clinical-trial referral and/or centralised multidisciplinary care.

    Presentations:

    • 15:18 - 15:31 CET
      Primary Urethral Carcinoma in 2026: Staging and Multimodality Pathways

      Speaker: Philippe E. Spiess – Moffitt Cancer Center

    • 15:31 CET
      Debate: “This House would perform pelvic lymph node dissection (rather than adjuvant pelvic radiotherapy/chemoradiotherapy or observation) for non-suspicious pelvic nodes but high-risk node-positive penile cancer after ILND.”

      Moderator: Manish Patel – University of Sydney

    • 15:31 - 15:41 CET
      For

      Speaker: Ben Ayres – St George's University Hospitals

    • 15:41 - 15:51 CET
      Against

      Speaker: Peter Johnstone

    • 15:51 - 15:56 CET
      Q&A
    • 15:56 - 16:11 CET
      New Developments in Systemic Therapy & Biomarkers in Penile Cancer: What’s Actionable Now and Who Should Go to Trials
    • 16:11 - 16:41 CET
      Penile Cancer Interactive Case Clinic

      Moderator: Gagan Prakash – Tata Memorial Hospital, Homi Bhabha National Institute

    • 16:41 - 16:45 CET
      Wrap-Up/Q&A